 USA: Delray Beach - Singles - Main |
|---|
| Quarter-finals | Korda S. | Isner J. | 2:1 (6:3, 4:6, 6:3) | details | 12.01.2021 |
| 1/8-finals | Monteiro T. | Isner J. | 0:2 (4:6, 64:7) | details | 10.01.2021 |
 France: French Open - Singles - Main |
|---|
| 1/32-finals | Korda S. | Isner J. | 3:1 (6:4, 6:4, 2:6, 6:4) | details | 30.09.2020 |
| 1/64-finals | Benchetrit E. | Isner J. | 0:3 (4:6, 1:6, 3:6) | details | 27.09.2020 |
| USA: US Open - Singles - Main |
|---|
| 1/64-finals | Johnson S. | Isner J. | 3:2 (65:7, 6:3, 65:7, 6:3, 7:63) | details | 01.09.2020 |
| USA: Cincinnati - Singles - Main |
|---|
| 1/8-finals | Isner J. | Tsitsipas S. | 0:2 (62:7, 64:7) | details | 25.08.2020 |
| 1/16-finals | Isner J. | Millman J. | 2:1 (4:6, 7:63, 7:65) | details | 24.08.2020 |
| 1/32-finals | Isner J. | Hurkacz H. | 2:0 (7:5, 6:4) | details | 23.08.2020 |
| USA: All-American Cup - Singles - Main |
|---|
| | Isner J. | Eubanks C. | 1:2 (5:7, 6:4, 6:10) | details | 05.07.2020 |
| | Isner J. | Tiafoe F. | CAN. | details | 05.07.2020 |
| | Isner J. | King K. | 2:0 (6:1, 6:3) | details | 05.07.2020 |
| | Isner J. | Opelka R. | CAN. | details | 05.07.2020 |
| | Isner J. | Fritz T. | 2:0 (6:3, 6:4) | details | 04.07.2020 |
 Mexico: Acapulco - Singles - Main |
|---|
| Semi-finals | Fritz T. | Isner J. | 2:1 (2:6, 7:5, 6:3) | details | 29.02.2020 |
| Quarter-finals | Isner J. | Paul T. | 2:1 (7:63, 3:6, 6:2) | details | 28.02.2020 |
| 1/8-finals | Isner J. | Giron M. | 2:0 (6:3, 7:64) | details | 27.02.2020 |
| 1/16-finals | Isner J. | Zverev M. | 2:0 (6:3, 7:64) | details | 26.02.2020 |
| USA: New York - Singles - Main |
|---|
| 1/8-finals | Isner J. | Thompson J. | 1:2 (62:7, 7:63, 3:6) | details | 14.02.2020 |
 Australia: Australian Open - Singles - Main |
|---|
| 1/16-finals | Isner J. | Wawrinka S. | 0:1 RET. (4:6, 1:4) | details | 25.01.2020 |
| 1/32-finals | Isner J. | Tabilo A. | 3:0 (6:4, 6:3, 6:3) | details | 23.01.2020 |
| 1/64-finals | Isner J. | Monteiro T. | 3:1 (65:7, 7:64, 7:67, 7:65) | details | 21.01.2020 |
 New Zealand: Auckland - Singles - Main |
|---|
| Semi-finals | Isner J. | Humbert U. | 0:2 (65:7, 4:6) | details | 17.01.2020 |
| Quarter-finals | Edmund K. | Isner J. | 0:2 (65:7, 65:7) | details | 16.01.2020 |
| 1/8-finals | Sandgren T. | Isner J. | 1:2 (63:7, 7:61, 3:6) | details | 15.01.2020 |
| Australia: ATP Cup - Singles - Main |
|---|
| | Fognini F. | Isner J. | 2:0 (6:4, 7:65) | details | 07.01.2020 |
| | Medvedev D. | Isner J. | 2:0 (6:3, 6:1) | details | 05.01.2020 |
| | Isner J. | Ruud C. | 1:2 (7:63, 610:7, 5:7) | details | 03.01.2020 |
 Saudi Arabia: Diriyah Tennis Cup - 5th-8th places |
|---|
| 5th place | Struff J-L. | Isner J. | 1:2 (6:4, 5:7, 11:13) | details | 14.12.2019 |
| Semi-finals | Isner J. | Wawrinka S. | 2:0 (7:64, 7:5) | details | 13.12.2019 |
| Saudi Arabia: Diriyah Tennis Cup - Main |
|---|
| Quarter-finals | Fognini F. | Isner J. | 2:0 (7:64, 6:4) | details | 12.12.2019 |
| France: Paris - Singles - Main |
|---|
| 1/16-finals | Garin C. | Isner J. | 2:0 (7:65, 7:64) | details | 30.10.2019 |
 China: Shanghai - Singles - Main |
|---|
| 1/8-finals | Djokovic N. | Isner J. | 2:0 (7:5, 6:3) | details | 10.10.2019 |
| 1/16-finals | Pouille L. | Isner J. | 0:2 (5:7, 3:6) | details | 09.10.2019 |
| 1/32-finals | De Minaur A. | Isner J. | 0:2 (61:7, 4:6) | details | 08.10.2019 |
| China: Beijing - Singles - Main |
|---|
| Quarter-finals | Isner J. | Tsitsipas S. | 0:2 (63:7, 3:6) | details | 04.10.2019 |
| 1/8-finals | Isner J. | Evans D. | 2:0 (7:63, 7:5) | details | 03.10.2019 |
| 1/16-finals | Monfils G. | Isner J. | 1:2 (4:6, 7:65, 3:6) | details | 01.10.2019 |
| China: Chengdu - Singles - Main |
|---|
| 1/8-finals | Isner J. | Gerasimov E. | 1:2 (7:611, 65:7, 64:7) | details | 26.09.2019 |
 World: Laver Cup - Singles - Main |
|---|
| | Federer R. | Isner J. | 2:0 (6:4, 7:63) | details | 22.09.2019 |
