 World: Billie Jean King Cup - World Group - Doubles - Qualification |
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| | Muhammad A./Pegula J. | Kichenok L./Yastremska D. | 2:0 (7:65, 6:3) | details | 16.04.2022 |
 Australia: Australian Open - Doubles - Main |
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| 1/16-finals | Collins D./Krawczyk D. | Muhammad A./Pegula J. | 2:0 (6:3, 7:62) | details | 22.01.2022 |
| 1/32-finals | Kovinic D./Krunic A. | Muhammad A./Pegula J. | 0:2 (1:6, 1:6) | details | 21.01.2022 |
| Australia: Melbourne (Summer Set 1) - Doubles - Main |
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| Final | Errani S./Paolini J. | Muhammad A./Pegula J. | 0:2 (3:6, 1:6) | details | 09.01.2022 |
| Semi-finals | Hruncakova V./Zvonareva V. | Muhammad A./Pegula J. | 1:2 (3:6, 7:62, 6:10) | details | 08.01.2022 |
| Quarter-finals | Lohoff J./Zimmermann K. | Muhammad A./Pegula J. | 0:2 (0:6, 5:7) | details | 07.01.2022 |
| 1/8-finals | Tauson C./Van Uytvanck A. | Muhammad A./Pegula J. | 0:2 (3:6, 2:6) | details | 05.01.2022 |
 USA: Indian Wells - Doubles - Main |
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| 1/8-finals | Muhammad A./Pegula J. | Aoyama S./Shibahara E. | 0:2 (3:6, 4:6) | details | 10.10.2021 |
| 1/16-finals | Kichenok N./Olaru R. | Muhammad A./Pegula J. | 1:2 (3:6, 6:3, 7:10) | details | 07.10.2021 |
| USA: Chicago 2 - Doubles - Main |
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| 1/16-finals | Linette M./Rosolska A. | Muhammad A./Pegula J. | 2:1 (1:6, 6:3, 10:8) | details | 28.09.2021 |
| USA: US Open - Doubles - Main |
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| 1/32-finals | Muhammad A./Pegula J. | Krueger A./Montgomery R. | 0:2 (2:6, 65:7) | details | 03.09.2021 |
 United Kingdom: Wimbledon - Doubles - Main |
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| 1/8-finals | Muhammad A./Pegula J. | Hsieh S-W./Mertens E. | 0:2 (5:7, 3:6) | details | 05.07.2021 |
| 1/16-finals | Muhammad A./Pegula J. | Kichenok L./Ninomiya M. | 2:0 (6:4, 6:4) | details | 03.07.2021 |
| 1/32-finals | Muhammad A./Pegula J. | Davis L./Raina A. | 2:0 (6:3, 6:2) | details | 01.07.2021 |
 Germany: Berlin - Doubles - Main |
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| Quarter-finals | Muhammad A./Pegula J. | Fichman S./Olmos G. | 1:2 (4:6, 6:1, 5:10) | details | 16.06.2021 |
| 1/8-finals | Muhammad A./Pegula J. | Muguruza G./Petkovic A. | 2:1 (2:6, 6:3, 10:5) | details | 14.06.2021 |
 France: French Open - Doubles - Main |
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| 1/16-finals | Muhammad A./Pegula J. | Hradecka L./Siegemund L. | 1:2 (6:4, 4:6, 0:6) | details | 04.06.2021 |
| 1/32-finals | Paolini J./Stojanovic N. | Muhammad A./Pegula J. | 1:2 (2:6, 6:2, 3:6) | details | 02.06.2021 |
| USA: Miami - Doubles - Main |
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| Quarter-finals | Carter H./Stefani L. | Muhammad A./Pegula J. | 2:0 (6:4, 6:1) | details | 30.03.2021 |
| 1/8-finals | Martic P./Rogers S. | Muhammad A./Pegula J. | 1:2 (6:4, 3:6, 3:10) | details | 28.03.2021 |
| 1/16-finals | Muhammad A./Pegula J. | Melichar-Martinez N./Schuurs D. | 2:0 (6:2, 6:2) | details | 27.03.2021 |
| Australia: Australian Open - Doubles - Main |
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| 1/32-finals | Aoyama S./Shibahara E. | Muhammad A./Pegula J. | 2:1 (4:6, 7:5, 6:3) | details | 10.02.2021 |
| Australia: Melbourne (Yarra Valley Classic) - Doubles - Main |
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| 1/16-finals | Kostyuk M./Sasnovich A. | Muhammad A./Pegula J. | 2:1 (6:2, 3:6, 10:8) | details | 02.02.2021 |
| France: French Open - Doubles - Main |
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| Quarter-finals | Muhammad A./Pegula J. | Melichar-Martinez N./Swiatek I. | 0:2 (3:6, 4:6) | details | 07.10.2020 |
| 1/8-finals | Muhammad A./Pegula J. | Gauff C./McNally C. | 2:0 (7:65, 6:3) | details | 04.10.2020 |
| 1/16-finals | Mertens E./Sabalenka A. | Muhammad A./Pegula J. | 1:2 (6:3, 1:6, 4:6) | details | 03.10.2020 |
