| Conference | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| # | Western Conference | MP | W | D | L | G | GD | Pts | Form |
| 1. | El Paso | 5 | 4 | 1 | 0 | 15:5 | 10 | 13 | |
| 2. | Rio Grande | 5 | 4 | 0 | 1 | 13:5 | 8 | 12 | |
| 3. | Orange County SC | 5 | 4 | 0 | 1 | 6:3 | 3 | 12 | |
| 4. | New Mexico | 5 | 3 | 2 | 0 | 12:6 | 6 | 11 | |
| 5. | Phoenix Rising | 5 | 3 | 2 | 0 | 9:4 | 5 | 11 | |
| 6. | San Diego Loyal | 5 | 3 | 1 | 1 | 11:8 | 3 | 10 | |
| 7. | Oakland Roots | 5 | 3 | 1 | 1 | 7:5 | 2 | 10 | |
| 8. | Colorado Springs | 5 | 2 | 3 | 0 | 6:3 | 3 | 9 | |
| 9. | Austin Bold | 5 | 2 | 3 | 0 | 6:4 | 2 | 9 | |
| 10. | San Antonio | 5 | 2 | 2 | 1 | 8:4 | 4 | 8 | |
| 11. | Tacoma Defiance | 5 | 2 | 1 | 2 | 8:6 | 2 | 7 | |
| 12. | Ventura County | 5 | 2 | 0 | 3 | 11:8 | 3 | 6 | |
| 13. | Sacramento Republic | 5 | 1 | 3 | 1 | 5:5 | 0 | 6 | |
| 14. | Real Monarchs | 5 | 1 | 3 | 1 | 6:7 | -1 | 6 | |
| 15. | Las Vegas Lights | 5 | 0 | 0 | 5 | 6:14 | -8 | 0 | |
| # | Eastern Conference | MP | W | D | L | G | GD | Pts | Form |
| 1. | Charlotte Independ. | 5 | 5 | 0 | 0 | 15:3 | 12 | 15 | |
| 2. | Memphis | 5 | 5 | 0 | 0 | 15:6 | 9 | 15 | |
| 3. | Tampa Bay | 5 | 4 | 1 | 0 | 17:3 | 14 | 13 | |
| 4. | Birmingham | 5 | 4 | 0 | 1 | 14:4 | 10 | 12 | |
| 5. | Louisville City | 5 | 4 | 0 | 1 | 12:7 | 5 | 12 | |
| 6. | Pittsburgh | 5 | 3 | 2 | 0 | 12:4 | 8 | 11 | |
| 7. | Miami FC | 5 | 3 | 1 | 1 | 12:5 | 7 | 10 | |
| 8. | Indy Eleven | 5 | 2 | 2 | 1 | 4:4 | 0 | 8 | |
| 9. | New York Red Bulls 2 | 5 | 2 | 1 | 2 | 9:8 | 1 | 7 | |
| 10. | FC Tulsa | 5 | 2 | 0 | 3 | 7:6 | 1 | 6 | |
| 11. | Hartford Athletic | 5 | 2 | 0 | 3 | 6:6 | 0 | 6 | |
| 12. | Charleston | 5 | 2 | 0 | 3 | 10:13 | -3 | 6 | |
| 13. | Oklahoma City Energy | 5 | 1 | 3 | 1 | 4:3 | 1 | 6 | |
| 14. | Sporting Kansas City II | 5 | 1 | 1 | 3 | 4:6 | -2 | 4 | |
| 15. | Loudoun | 5 | 1 | 0 | 4 | 6:15 | -9 | 3 | |
| 16. | Atlanta United 2 | 5 | 0 | 3 | 2 | 4:10 | -6 | 3 | |
| Division | |||||||||
| # | Atlantic Division | MP | W | D | L | G | GD | Pts | Form |
| 1. | Charlotte Independ. | 5 | 5 | 0 | 0 | 15:3 | 12 | 15 | |
| 2. | Tampa Bay | 5 | 4 | 1 | 0 | 17:3 | 14 | 13 | |
| 3. | Pittsburgh | 5 | 3 | 2 | 0 | 12:4 | 8 | 11 | |
| 4. | Miami FC | 5 | 3 | 1 | 1 | 12:5 | 7 | 10 | |
| 5. | New York Red Bulls 2 | 5 | 2 | 1 | 2 | 9:8 | 1 | 7 | |
| 6. | Hartford Athletic | 5 | 2 | 0 | 3 | 6:6 | 0 | 6 | |
| 7. | Charleston | 5 | 2 | 0 | 3 | 10:13 | -3 | 6 | |
| 8. | Loudoun | 5 | 1 | 0 | 4 | 6:15 | -9 | 3 | |
| # | Central Division | MP | W | D | L | G | GD | Pts | Form |
| 1. | Memphis | 5 | 5 | 0 | 0 | 15:6 | 9 | 15 | |
| 2. | Birmingham | 5 | 4 | 0 | 1 | 14:4 | 10 | 12 | |
| 3. | Louisville City | 5 | 4 | 0 | 1 | 12:7 | 5 | 12 | |
| 4. | Indy Eleven | 5 | 2 | 2 | 1 | 4:4 | 0 | 8 | |
| 5. | FC Tulsa | 5 | 2 | 0 | 3 | 7:6 | 1 | 6 | |
| 6. | Oklahoma City Energy | 5 | 1 | 3 | 1 | 4:3 | 1 | 6 | |
| 7. | Sporting Kansas City II | 5 | 1 | 1 | 3 | 4:6 | -2 | 4 | |
| 8. | Atlanta United 2 | 5 | 0 | 3 | 2 | 4:10 | -6 | 3 | |
| # | Pacific Division | MP | W | D | L | G | GD | Pts | Form |
| 1. | Orange County SC | 5 | 4 | 0 | 1 | 6:3 | 3 | 12 | |
| 2. | Phoenix Rising | 5 | 3 | 2 | 0 | 9:4 | 5 | 11 | |
| 3. | San Diego Loyal | 5 | 3 | 1 | 1 | 11:8 | 3 | 10 | |
| 4. | Oakland Roots | 5 | 3 | 1 | 1 | 7:5 | 2 | 10 | |
| 5. | Tacoma Defiance | 5 | 2 | 1 | 2 | 8:6 | 2 | 7 | |
| 6. | Ventura County | 5 | 2 | 0 | 3 | 11:8 | 3 | 6 | |
| 7. | Sacramento Republic | 5 | 1 | 3 | 1 | 5:5 | 0 | 6 | |
| 8. | Las Vegas Lights | 5 | 0 | 0 | 5 | 6:14 | -8 | 0 | |
| # | Mountain Division | MP | W | D | L | G | GD | Pts | Form |
| 1. | El Paso | 5 | 4 | 1 | 0 | 15:5 | 10 | 13 | |
| 2. | Rio Grande | 5 | 4 | 0 | 1 | 13:5 | 8 | 12 | |
| 3. | New Mexico | 5 | 3 | 2 | 0 | 12:6 | 6 | 11 | |
| 4. | Colorado Springs | 5 | 2 | 3 | 0 | 6:3 | 3 | 9 | |
| 5. | Austin Bold | 5 | 2 | 3 | 0 | 6:4 | 2 | 9 | |
| 6. | San Antonio | 5 | 2 | 2 | 1 | 8:4 | 4 | 8 | |
| 7. | Real Monarchs | 5 | 1 | 3 | 1 | 6:7 | -1 | 6 | |
| Conference | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| # | Western Conference | MP | W | D | L | G | GD | Pts | Form |
| 1. | El Paso | 10 | 9 | 1 | 0 | 28:7 | 21 | 28 | |
| 2. | Phoenix Rising | 10 | 6 | 4 | 0 | 21:8 | 13 | 22 | |
| 3. | Oakland Roots | 10 | 6 | 2 | 2 | 16:9 | 7 | 20 | |
| 4. | New Mexico | 10 | 5 | 5 | 0 | 19:11 | 8 | 20 | |
| 5. | Colorado Springs | 10 | 5 | 4 | 1 | 19:10 | 9 | 19 | |
| 6. | San Antonio | 10 | 5 | 3 | 2 | 18:10 | 8 | 18 | |
| 7. | Austin Bold | 10 | 4 | 6 | 0 | 12:8 | 4 | 18 | |
| 8. | Rio Grande | 10 | 5 | 2 | 3 | 21:16 | 5 | 17 | |
| 9. | Orange County SC | 10 | 5 | 2 | 3 | 15:13 | 2 | 17 | |
| 10. | Tacoma Defiance | 10 | 4 | 2 | 4 | 15:13 | 2 | 14 | |
| 11. | San Diego Loyal | 10 | 4 | 1 | 5 | 18:15 | 3 | 13 | |
| 12. | Ventura County | 10 | 3 | 3 | 4 | 19:15 | 4 | 12 | |
| 13. | Sacramento Republic | 10 | 3 | 3 | 4 | 11:13 | -2 | 12 | |
| 14. | Real Monarchs | 10 | 3 | 3 | 4 | 13:18 | -5 | 12 | |
| 15. | Las Vegas Lights | 10 | 1 | 1 | 8 | 15:26 | -11 | 4 | |
| # | Eastern Conference | MP | W | D | L | G | GD | Pts | Form |
| 1. | Charlotte Independ. | 10 | 8 | 2 | 0 | 24:8 | 16 | 26 | |
| 2. | Tampa Bay | 10 | 8 | 1 | 1 | 24:5 | 19 | 25 | |
| 3. | Miami FC | 10 | 8 | 1 | 1 | 24:9 | 15 | 25 | |
| 4. | Louisville City | 10 | 8 | 1 | 1 | 26:13 | 13 | 25 | |
| 5. | Birmingham | 10 | 7 | 1 | 2 | 25:11 | 14 | 22 | |
| 6. | Memphis | 10 | 7 | 1 | 2 | 20:12 | 8 | 22 | |
| 7. | Pittsburgh | 10 | 6 | 3 | 1 | 22:9 | 13 | 21 | |
| 8. | FC Tulsa | 10 | 6 | 1 | 3 | 18:11 | 7 | 19 | |
| 9. | Indy Eleven | 10 | 4 | 3 | 3 | 10:9 | 1 | 15 | |
| 10. | Oklahoma City Energy | 10 | 3 | 6 | 1 | 10:5 | 5 | 15 | |
| 11. | Hartford Athletic | 10 | 4 | 1 | 5 | 15:15 | 0 | 13 | |
| 12. | Charleston | 10 | 4 | 1 | 5 | 15:17 | -2 | 13 | |
| 13. | Atlanta United 2 | 10 | 2 | 5 | 3 | 15:17 | -2 | 11 | |
| 14. | New York Red Bulls 2 | 10 | 2 | 2 | 6 | 16:20 | -4 | 8 | |
| 15. | Loudoun | 10 | 2 | 1 | 7 | 14:26 | -12 | 7 | |
| 16. | Sporting Kansas City II | 10 | 1 | 3 | 6 | 8:15 | -7 | 6 | |
| Division | |||||||||
| # | Atlantic Division | MP | W | D | L | G | GD | Pts | Form |
| 1. | Charlotte Independ. | 10 | 8 | 2 | 0 | 24:8 | 16 | 26 | |
| 2. | Tampa Bay | 10 | 8 | 1 | 1 | 24:5 | 19 | 25 | |
| 3. | Miami FC | 10 | 8 | 1 | 1 | 24:9 | 15 | 25 | |
| 4. | Pittsburgh | 10 | 6 | 3 | 1 | 22:9 | 13 | 21 | |
| 5. | Hartford Athletic | 10 | 4 | 1 | 5 | 15:15 | 0 | 13 | |
| 6. | Charleston | 10 | 4 | 1 | 5 | 15:17 | -2 | 13 | |
| 7. | New York Red Bulls 2 | 10 | 2 | 2 | 6 | 16:20 | -4 | 8 | |
| 8. | Loudoun | 10 | 2 | 1 | 7 | 14:26 | -12 | 7 | |
| # | Central Division | MP | W | D | L | G | GD | Pts | Form |
| 1. | Louisville City | 10 | 8 | 1 | 1 | 26:13 | 13 | 25 | |
| 2. | Birmingham | 10 | 7 | 1 | 2 | 25:11 | 14 | 22 | |
| 3. | Memphis | 10 | 7 | 1 | 2 | 20:12 | 8 | 22 | |
| 4. | FC Tulsa | 10 | 6 | 1 | 3 | 18:11 | 7 | 19 | |
| 5. | Indy Eleven | 10 | 4 | 3 | 3 | 10:9 | 1 | 15 | |
| 6. | Oklahoma City Energy | 10 | 3 | 6 | 1 | 10:5 | 5 | 15 | |
| 7. | Atlanta United 2 | 10 | 2 | 5 | 3 | 15:17 | -2 | 11 | |
| 8. | Sporting Kansas City II | 10 | 1 | 3 | 6 | 8:15 | -7 | 6 | |
| # | Pacific Division | MP | W | D | L | G | GD | Pts | Form |
| 1. | Phoenix Rising | 10 | 6 | 4 | 0 | 21:8 | 13 | 22 | |
| 2. | Oakland Roots | 10 | 6 | 2 | 2 | 16:9 | 7 | 20 | |
| 3. | Orange County SC | 10 | 5 | 2 | 3 | 15:13 | 2 | 17 | |
| 4. | Tacoma Defiance | 10 | 4 | 2 | 4 | 15:13 | 2 | 14 | |
| 5. | San Diego Loyal | 10 | 4 | 1 | 5 | 18:15 | 3 | 13 | |
| 6. | Ventura County | 10 | 3 | 3 | 4 | 19:15 | 4 | 12 | |
| 7. | Sacramento Republic | 10 | 3 | 3 | 4 | 11:13 | -2 | 12 | |
| 8. | Las Vegas Lights | 10 | 1 | 1 | 8 | 15:26 | -11 | 4 | |
| # | Mountain Division | MP | W | D | L | G | GD | Pts | Form |
| 1. | El Paso | 10 | 9 | 1 | 0 | 28:7 | 21 | 28 | |
| 2. | New Mexico | 10 | 5 | 5 | 0 | 19:11 | 8 | 20 | |
| 3. | Colorado Springs | 10 | 5 | 4 | 1 | 19:10 | 9 | 19 | |
| 4. | San Antonio | 10 | 5 | 3 | 2 | 18:10 | 8 | 18 | |
| 5. | Austin Bold | 10 | 4 | 6 | 0 | 12:8 | 4 | 18 | |
| 6. | Rio Grande | 10 | 5 | 2 | 3 | 21:16 | 5 | 17 | |
| 7. | Real Monarchs | 10 | 3 | 3 | 4 | 13:18 | -5 | 12 | |
| Conference | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| # | Western Conference | MP | W | D | L | G | GD | Pts | Form |
| 1. | El Paso | 15 | 13 | 2 | 0 | 35:9 | 26 | 41 | |
| 2. | Phoenix Rising | 15 | 10 | 5 | 0 | 37:11 | 26 | 35 | |
| 3. | New Mexico | 15 | 8 | 6 | 1 | 26:14 | 12 | 30 | |
| 4. | Colorado Springs | 15 | 8 | 5 | 2 | 30:17 | 13 | 29 | |
| 5. | San Diego Loyal | 15 | 8 | 2 | 5 | 26:19 | 7 | 26 | |
| 6. | Rio Grande | 15 | 8 | 2 | 5 | 27:21 | 6 | 26 | |
| 7. | Tacoma Defiance | 15 | 7 | 4 | 4 | 21:15 | 6 | 25 | |
| 8. | Oakland Roots | 15 | 7 | 3 | 5 | 19:16 | 3 | 24 | |
| 9. | San Antonio | 15 | 6 | 6 | 3 | 24:16 | 8 | 24 | |
| 10. | Orange County SC | 15 | 6 | 4 | 5 | 20:20 | 0 | 22 | |
| 11. | Austin Bold | 15 | 5 | 7 | 3 | 16:16 | 0 | 22 | |
| 12. | Ventura County | 15 | 4 | 5 | 6 | 31:24 | 7 | 17 | |
| 13. | Real Monarchs | 15 | 4 | 5 | 6 | 18:23 | -5 | 17 | |
| 14. | Sacramento Republic | 15 | 3 | 5 | 7 | 16:22 | -6 | 14 | |
| 15. | Las Vegas Lights | 15 | 2 | 2 | 11 | 20:34 | -14 | 8 | |
| # | Eastern Conference | MP | W | D | L | G | GD | Pts | Form |
| 1. | Tampa Bay | 15 | 12 | 1 | 2 | 34:10 | 24 | 37 | |
| 2. | Charlotte Independ. | 15 | 11 | 3 | 1 | 35:14 | 21 | 36 | |
| 3. | Louisville City | 15 | 11 | 2 | 2 | 35:17 | 18 | 35 | |
| 4. | Birmingham | 15 | 10 | 2 | 3 | 31:15 | 16 | 32 | |
| 5. | Miami FC | 15 | 10 | 1 | 4 | 30:17 | 13 | 31 | |
| 6. | Pittsburgh | 15 | 9 | 4 | 2 | 27:12 | 15 | 31 | |
| 7. | Memphis | 15 | 8 | 3 | 4 | 25:18 | 7 | 27 | |
| 8. | FC Tulsa | 15 | 8 | 1 | 6 | 28:23 | 5 | 25 | |
| 9. | Charleston | 15 | 7 | 3 | 5 | 26:22 | 4 | 24 | |
| 10. | Hartford Athletic | 15 | 7 | 2 | 6 | 28:19 | 9 | 23 | |
| 11. | Oklahoma City Energy | 15 | 4 | 8 | 3 | 14:10 | 4 | 20 | |
| 12. | Indy Eleven | 15 | 5 | 4 | 6 | 14:14 | 0 | 19 | |
| 13. | Atlanta United 2 | 15 | 3 | 7 | 5 | 21:24 | -3 | 16 | |
| 14. | New York Red Bulls 2 | 15 | 3 | 3 | 9 | 20:27 | -7 | 12 | |
| 15. | Loudoun | 15 | 3 | 1 | 11 | 19:37 | -18 | 10 | |
| 16. | Sporting Kansas City II | 15 | 2 | 4 | 9 | 15:26 | -11 | 10 | |
| Division | |||||||||
| # | Atlantic Division | MP | W | D | L | G | GD | Pts | Form |
| 1. | Tampa Bay | 15 | 12 | 1 | 2 | 34:10 | 24 | 37 | |
| 2. | Charlotte Independ. | 15 | 11 | 3 | 1 | 35:14 | 21 | 36 | |
| 3. | Miami FC | 15 | 10 | 1 | 4 | 30:17 | 13 | 31 | |
| 4. | Pittsburgh | 15 | 9 | 4 | 2 | 27:12 | 15 | 31 | |
| 5. | Charleston | 15 | 7 | 3 | 5 | 26:22 | 4 | 24 | |
| 6. | Hartford Athletic | 15 | 7 | 2 | 6 | 28:19 | 9 | 23 | |
| 7. | New York Red Bulls 2 | 15 | 3 | 3 | 9 | 20:27 | -7 | 12 | |
| 8. | Loudoun | 15 | 3 | 1 | 11 | 19:37 | -18 | 10 | |
| # | Central Division | MP | W | D | L | G | GD | Pts | Form |
| 1. | Louisville City | 15 | 11 | 2 | 2 | 35:17 | 18 | 35 | |
| 2. | Birmingham | 15 | 10 | 2 | 3 | 31:15 | 16 | 32 | |
| 3. | Memphis | 15 | 8 | 3 | 4 | 25:18 | 7 | 27 | |
| 4. | FC Tulsa | 15 | 8 | 1 | 6 | 28:23 | 5 | 25 | |
| 5. | Oklahoma City Energy | 15 | 4 | 8 | 3 | 14:10 | 4 | 20 | |
| 6. | Indy Eleven | 15 | 5 | 4 | 6 | 14:14 | 0 | 19 | |
| 7. | Atlanta United 2 | 15 | 3 | 7 | 5 | 21:24 | -3 | 16 | |
| 8. | Sporting Kansas City II | 15 | 2 | 4 | 9 | 15:26 | -11 | 10 | |
| # | Pacific Division | MP | W | D | L | G | GD | Pts | Form |
| 1. | Phoenix Rising | 15 | 10 | 5 | 0 | 37:11 | 26 | 35 | |
| 2. | San Diego Loyal | 15 | 8 | 2 | 5 | 26:19 | 7 | 26 | |
| 3. | Tacoma Defiance | 15 | 7 | 4 | 4 | 21:15 | 6 | 25 | |
| 4. | Oakland Roots | 15 | 7 | 3 | 5 | 19:16 | 3 | 24 | |
| 5. | Orange County SC | 15 | 6 | 4 | 5 | 20:20 | 0 | 22 | |
| 6. | Ventura County | 15 | 4 | 5 | 6 | 31:24 | 7 | 17 | |
| 7. | Sacramento Republic | 15 | 3 | 5 | 7 | 16:22 | -6 | 14 | |
| 8. | Las Vegas Lights | 15 | 2 | 2 | 11 | 20:34 | -14 | 8 | |
| # | Mountain Division | MP | W | D | L | G | GD | Pts | Form |
| 1. | El Paso | 15 | 13 | 2 | 0 | 35:9 | 26 | 41 | |
| 2. | New Mexico | 15 | 8 | 6 | 1 | 26:14 | 12 | 30 | |
| 3. | Colorado Springs | 15 | 8 | 5 | 2 | 30:17 | 13 | 29 | |
| 4. | Rio Grande | 15 | 8 | 2 | 5 | 27:21 | 6 | 26 | |
| 5. | San Antonio | 15 | 6 | 6 | 3 | 24:16 | 8 | 24 | |
| 6. | Austin Bold | 15 | 5 | 7 | 3 | 16:16 | 0 | 22 | |
| 7. | Real Monarchs | 15 | 4 | 5 | 6 | 18:23 | -5 | 17 | |
| Conference | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| # | Western Conference | MP | W | D | L | G | GD | Pts | Form |
| 1. | El Paso | 16 | 13 | 3 | 0 | 36:10 | 26 | 42 | |
| 2. | Phoenix Rising | 16 | 11 | 5 | 0 | 41:12 | 29 | 38 | |
| 3. | New Mexico | 16 | 9 | 6 | 1 | 29:15 | 14 | 33 | |
| 4. | San Diego Loyal | 16 | 9 | 2 | 5 | 28:20 | 8 | 29 | |
| 5. | Rio Grande | 16 | 9 | 2 | 5 | 28:21 | 7 | 29 | |
| 6. | Colorado Springs | 16 | 8 | 5 | 3 | 31:20 | 11 | 29 | |
| 7. | Tacoma Defiance | 16 | 8 | 4 | 4 | 24:16 | 8 | 28 | |
| 8. | San Antonio | 16 | 7 | 6 | 3 | 27:16 | 11 | 27 | |
| 9. | Oakland Roots | 16 | 7 | 4 | 5 | 19:16 | 3 | 25 | |
| 10. | Orange County SC | 16 | 7 | 4 | 5 | 21:20 | 1 | 25 | |
| 11. | Austin Bold | 16 | 6 | 7 | 3 | 18:16 | 2 | 25 | |
| 12. | Ventura County | 16 | 4 | 5 | 7 | 31:25 | 6 | 17 | |
| 13. | Sacramento Republic | 16 | 4 | 5 | 7 | 19:23 | -4 | 17 | |
| 14. | Real Monarchs | 16 | 4 | 5 | 7 | 18:25 | -7 | 17 | |
| 15. | Las Vegas Lights | 16 | 3 | 2 | 11 | 22:34 | -12 | 11 | |
| # | Eastern Conference | MP | W | D | L | G | GD | Pts | Form |
| 1. | Tampa Bay | 16 | 13 | 1 | 2 | 37:10 | 27 | 40 | |
| 2. | Charlotte Independ. | 16 | 12 | 3 | 1 | 36:14 | 22 | 39 | |
| 3. | Louisville City | 16 | 12 | 2 | 2 | 37:17 | 20 | 38 | |
| 4. | Miami FC | 16 | 11 | 1 | 4 | 32:18 | 14 | 34 | |
| 5. | Birmingham | 16 | 10 | 2 | 4 | 31:16 | 15 | 32 | |
| 6. | Pittsburgh | 16 | 9 | 4 | 3 | 27:13 | 14 | 31 | |
| 7. | Memphis | 16 | 9 | 3 | 4 | 26:18 | 8 | 30 | |
| 8. | FC Tulsa | 16 | 9 | 1 | 6 | 30:23 | 7 | 28 | |
| 9. | Hartford Athletic | 16 | 7 | 3 | 6 | 29:20 | 9 | 24 | |
| 10. | Charleston | 16 | 7 | 3 | 6 | 26:25 | 1 | 24 | |
| 11. | Oklahoma City Energy | 16 | 4 | 8 | 4 | 15:13 | 2 | 20 | |
| 12. | Indy Eleven | 16 | 5 | 4 | 7 | 14:16 | -2 | 19 | |
| 13. | Atlanta United 2 | 16 | 4 | 7 | 5 | 26:24 | 2 | 19 | |
| 14. | New York Red Bulls 2 | 16 | 3 | 3 | 10 | 22:30 | -8 | 12 | |
| 15. | Sporting Kansas City II | 16 | 2 | 5 | 9 | 16:27 | -11 | 11 | |
| 16. | Loudoun | 16 | 3 | 1 | 12 | 20:39 | -19 | 10 | |
| Division | |||||||||
| # | Atlantic Division | MP | W | D | L | G | GD | Pts | Form |
| 1. | Tampa Bay | 16 | 13 | 1 | 2 | 37:10 | 27 | 40 | |
| 2. | Charlotte Independ. | 16 | 12 | 3 | 1 | 36:14 | 22 | 39 | |
| 3. | Miami FC | 16 | 11 | 1 | 4 | 32:18 | 14 | 34 | |
| 4. | Pittsburgh | 16 | 9 | 4 | 3 | 27:13 | 14 | 31 | |
| 5. | Hartford Athletic | 16 | 7 | 3 | 6 | 29:20 | 9 | 24 | |
| 6. | Charleston | 16 | 7 | 3 | 6 | 26:25 | 1 | 24 | |
| 7. | New York Red Bulls 2 | 16 | 3 | 3 | 10 | 22:30 | -8 | 12 | |
| 8. | Loudoun | 16 | 3 | 1 | 12 | 20:39 | -19 | 10 | |
| # | Central Division | MP | W | D | L | G | GD | Pts | Form |
| 1. | Louisville City | 16 | 12 | 2 | 2 | 37:17 | 20 | 38 | |
| 2. | Birmingham | 16 | 10 | 2 | 4 | 31:16 | 15 | 32 | |
| 3. | Memphis | 16 | 9 | 3 | 4 | 26:18 | 8 | 30 | |
| 4. | FC Tulsa | 16 | 9 | 1 | 6 | 30:23 | 7 | 28 | |
| 5. | Oklahoma City Energy | 16 | 4 | 8 | 4 | 15:13 | 2 | 20 | |
| 6. | Indy Eleven | 16 | 5 | 4 | 7 | 14:16 | -2 | 19 | |
| 7. | Atlanta United 2 | 16 | 4 | 7 | 5 | 26:24 | 2 | 19 | |
| 8. | Sporting Kansas City II | 16 | 2 | 5 | 9 | 16:27 | -11 | 11 | |
| # | Pacific Division | MP | W | D | L | G | GD | Pts | Form |
| 1. | Phoenix Rising | 16 | 11 | 5 | 0 | 41:12 | 29 | 38 | |
| 2. | San Diego Loyal | 16 | 9 | 2 | 5 | 28:20 | 8 | 29 | |
| 3. | Tacoma Defiance | 16 | 8 | 4 | 4 | 24:16 | 8 | 28 | |
| 4. | Oakland Roots | 16 | 7 | 4 | 5 | 19:16 | 3 | 25 | |
| 5. | Orange County SC | 16 | 7 | 4 | 5 | 21:20 | 1 | 25 | |
| 6. | Ventura County | 16 | 4 | 5 | 7 | 31:25 | 6 | 17 | |
| 7. | Sacramento Republic | 16 | 4 | 5 | 7 | 19:23 | -4 | 17 | |
| 8. | Las Vegas Lights | 16 | 3 | 2 | 11 | 22:34 | -12 | 11 | |
| # | Mountain Division | MP | W | D | L | G | GD | Pts | Form |
| 1. | El Paso | 16 | 13 | 3 | 0 | 36:10 | 26 | 42 | |
| 2. | New Mexico | 16 | 9 | 6 | 1 | 29:15 | 14 | 33 | |
| 3. | Rio Grande | 16 | 9 | 2 | 5 | 28:21 | 7 | 29 | |
| 4. | Colorado Springs | 16 | 8 | 5 | 3 | 31:20 | 11 | 29 | |
| 5. | San Antonio | 16 | 7 | 6 | 3 | 27:16 | 11 | 27 | |
| 6. | Austin Bold | 16 | 6 | 7 | 3 | 18:16 | 2 | 25 | |
| 7. | Real Monarchs | 16 | 4 | 5 | 7 | 18:25 | -7 | 17 | |