| # | Eastern Conference | MP | W | D | L | G | GD | Pts | Form |
|---|---|---|---|---|---|---|---|---|---|
| 1. | Pittsburgh | 5 | 5 | 0 | 0 | 11:4 | 7 | 15 | |
| 2. | Indy Eleven | 5 | 4 | 0 | 1 | 10:2 | 8 | 12 | |
| 3. | Charleston | 5 | 4 | 0 | 1 | 7:3 | 4 | 12 | |
| 4. | Memphis | 5 | 3 | 0 | 2 | 12:7 | 5 | 9 | |
| 5. | Tampa Bay | 5 | 3 | 0 | 2 | 7:8 | -1 | 9 | |
| 6. | Louisville City | 5 | 2 | 2 | 1 | 8:7 | 1 | 8 | |
| 7. | Detroit | 5 | 2 | 2 | 1 | 6:5 | 1 | 8 | |
| 8. | Birmingham | 5 | 2 | 1 | 2 | 6:6 | 0 | 7 | |
| 9. | Miami FC | 5 | 2 | 0 | 3 | 7:8 | -1 | 6 | |
| 10. | FC Tulsa | 5 | 1 | 1 | 3 | 5:8 | -3 | 4 | |
| 11. | Loudoun | 5 | 0 | 2 | 3 | 4:10 | -6 | 2 | |
| 12. | Hartford Athletic | 5 | 0 | 1 | 4 | 7:15 | -8 | 1 | |
| # | Western Conference | MP | W | D | L | G | GD | Pts | Form |
| 1. | San Diego Loyal | 5 | 3 | 2 | 0 | 14:6 | 8 | 11 | |
| 2. | New Mexico | 5 | 3 | 1 | 1 | 12:7 | 5 | 10 | |
| 3. | Orange County SC | 5 | 3 | 1 | 1 | 6:2 | 4 | 10 | |
| 4. | Sacramento Republic | 5 | 3 | 1 | 1 | 4:2 | 2 | 10 | |
| 5. | Phoenix Rising | 5 | 2 | 2 | 1 | 10:4 | 6 | 8 | |
| 6. | Colorado Springs | 5 | 2 | 2 | 1 | 8:5 | 3 | 8 | |
| 7. | Rio Grande | 5 | 2 | 1 | 2 | 7:7 | 0 | 7 | |
| 8. | San Antonio | 5 | 1 | 4 | 0 | 10:6 | 4 | 7 | |
| 9. | Monterey Bay | 5 | 2 | 0 | 3 | 7:8 | -1 | 6 | |
| 10. | El Paso | 5 | 1 | 2 | 2 | 7:8 | -1 | 5 | |
| 11. | Las Vegas Lights | 5 | 1 | 0 | 4 | 6:12 | -6 | 3 | |
| 12. | Oakland Roots | 5 | 0 | 2 | 3 | 5:8 | -3 | 2 |
| # | Eastern Conference | MP | W | D | L | G | GD | Pts | Form |
|---|---|---|---|---|---|---|---|---|---|
| 1. | Pittsburgh | 10 | 7 | 2 | 1 | 18:9 | 9 | 23 | |
| 2. | Tampa Bay | 10 | 7 | 1 | 2 | 21:12 | 9 | 22 | |
| 3. | Charleston | 10 | 6 | 1 | 3 | 13:9 | 4 | 19 | |
| 4. | Detroit | 10 | 5 | 3 | 2 | 11:7 | 4 | 18 | |
| 5. | Birmingham | 10 | 5 | 2 | 3 | 13:9 | 4 | 17 | |
| 6. | Memphis | 10 | 5 | 1 | 4 | 22:17 | 5 | 16 | |
| 7. | FC Tulsa | 10 | 5 | 1 | 4 | 14:16 | -2 | 16 | |
| 8. | Indy Eleven | 10 | 4 | 3 | 3 | 14:8 | 6 | 15 | |
| 9. | Louisville City | 10 | 4 | 3 | 3 | 13:11 | 2 | 15 | |
| 10. | Miami FC | 10 | 4 | 2 | 4 | 15:12 | 3 | 14 | |
| 11. | Loudoun | 10 | 2 | 2 | 6 | 13:21 | -8 | 8 | |
| 12. | Hartford Athletic | 10 | 1 | 1 | 8 | 12:27 | -15 | 4 | |
| # | Western Conference | MP | W | D | L | G | GD | Pts | Form |
| 1. | Orange County SC | 10 | 7 | 1 | 2 | 13:4 | 9 | 22 | |
| 2. | Rio Grande | 10 | 6 | 2 | 2 | 19:12 | 7 | 20 | |
| 3. | New Mexico | 10 | 6 | 1 | 3 | 19:13 | 6 | 19 | |
| 4. | Phoenix Rising | 10 | 5 | 3 | 2 | 25:8 | 17 | 18 | |
| 5. | San Diego Loyal | 10 | 5 | 3 | 2 | 21:13 | 8 | 18 | |
| 6. | Sacramento Republic | 10 | 5 | 3 | 2 | 13:6 | 7 | 18 | |
| 7. | Colorado Springs | 10 | 5 | 3 | 2 | 17:12 | 5 | 18 | |
| 8. | San Antonio | 10 | 4 | 5 | 1 | 22:13 | 9 | 17 | |
| 9. | Monterey Bay | 10 | 4 | 1 | 5 | 13:14 | -1 | 13 | |
| 10. | El Paso | 10 | 1 | 4 | 5 | 11:16 | -5 | 7 | |
| 11. | Oakland Roots | 10 | 1 | 4 | 5 | 10:15 | -5 | 7 | |
| 12. | Las Vegas Lights | 10 | 2 | 0 | 8 | 11:23 | -12 | 6 |
| # | Eastern Conference | MP | W | D | L | G | GD | Pts | Form |
|---|---|---|---|---|---|---|---|---|---|
| 1. | Pittsburgh | 15 | 12 | 2 | 1 | 29:12 | 17 | 38 | |
| 2. | Tampa Bay | 15 | 11 | 1 | 3 | 33:16 | 17 | 34 | |
| 3. | Charleston | 15 | 8 | 2 | 5 | 18:20 | -2 | 26 | |
| 4. | Memphis | 15 | 7 | 4 | 4 | 32:22 | 10 | 25 | |
| 5. | Detroit | 15 | 7 | 4 | 4 | 14:10 | 4 | 25 | |
| 6. | Louisville City | 15 | 7 | 3 | 5 | 20:17 | 3 | 24 | |
| 7. | Birmingham | 15 | 7 | 2 | 6 | 21:20 | 1 | 23 | |
| 8. | Miami FC | 15 | 6 | 4 | 5 | 25:18 | 7 | 22 | |
| 9. | Indy Eleven | 15 | 5 | 5 | 5 | 19:14 | 5 | 20 | |
| 10. | FC Tulsa | 15 | 5 | 3 | 7 | 19:26 | -7 | 18 | |
| 11. | Loudoun | 15 | 4 | 2 | 9 | 20:27 | -7 | 14 | |
| 12. | Hartford Athletic | 15 | 2 | 2 | 11 | 16:36 | -20 | 8 | |
| # | Western Conference | MP | W | D | L | G | GD | Pts | Form |
| 1. | Sacramento Republic | 15 | 10 | 3 | 2 | 29:8 | 21 | 33 | |
| 2. | Orange County SC | 15 | 9 | 2 | 4 | 19:10 | 9 | 29 | |
| 3. | Colorado Springs | 15 | 8 | 3 | 4 | 27:17 | 10 | 27 | |
| 4. | New Mexico | 15 | 8 | 2 | 5 | 26:21 | 5 | 26 | |
| 5. | Phoenix Rising | 15 | 7 | 5 | 3 | 35:15 | 20 | 26 | |
| 6. | San Diego Loyal | 15 | 7 | 4 | 4 | 28:20 | 8 | 25 | |
| 7. | San Antonio | 15 | 5 | 9 | 1 | 29:19 | 10 | 24 | |
| 8. | Rio Grande | 15 | 6 | 4 | 5 | 22:23 | -1 | 22 | |
| 9. | Monterey Bay | 15 | 5 | 4 | 6 | 20:20 | 0 | 19 | |
| 10. | El Paso | 15 | 5 | 4 | 6 | 18:20 | -2 | 19 | |
| 11. | Oakland Roots | 15 | 3 | 7 | 5 | 16:16 | 0 | 16 | |
| 12. | Las Vegas Lights | 15 | 2 | 3 | 10 | 19:33 | -14 | 9 |
| # | Eastern Conference | MP | W | D | L | G | GD | Pts | Form |
|---|---|---|---|---|---|---|---|---|---|
| 1. | Pittsburgh | 17 | 13 | 3 | 1 | 32:13 | 19 | 42 | |
| 2. | Tampa Bay | 17 | 11 | 2 | 4 | 34:19 | 15 | 35 | |
| 3. | Charleston | 17 | 9 | 3 | 5 | 22:21 | 1 | 30 | |
| 4. | Birmingham | 17 | 8 | 3 | 6 | 25:23 | 2 | 27 | |
| 5. | Louisville City | 17 | 8 | 3 | 6 | 21:20 | 1 | 27 | |
| 6. | Memphis | 17 | 7 | 4 | 6 | 34:28 | 6 | 25 | |
| 7. | Detroit | 17 | 7 | 4 | 6 | 14:12 | 2 | 25 | |
| 8. | Miami FC | 17 | 6 | 5 | 6 | 26:20 | 6 | 23 | |
| 9. | FC Tulsa | 17 | 6 | 4 | 7 | 22:26 | -4 | 22 | |
| 10. | Indy Eleven | 17 | 5 | 6 | 6 | 19:17 | 2 | 21 | |
| 11. | Loudoun | 17 | 4 | 3 | 10 | 21:29 | -8 | 15 | |
| 12. | Hartford Athletic | 17 | 2 | 3 | 12 | 17:38 | -21 | 9 | |
| # | Western Conference | MP | W | D | L | G | GD | Pts | Form |
| 1. | Sacramento Republic | 17 | 11 | 4 | 2 | 31:9 | 22 | 37 | |
| 2. | San Diego Loyal | 17 | 9 | 4 | 4 | 32:20 | 12 | 31 | |
| 3. | Colorado Springs | 17 | 9 | 4 | 4 | 29:18 | 11 | 31 | |
| 4. | New Mexico | 17 | 9 | 3 | 5 | 30:23 | 7 | 30 | |
| 5. | Orange County SC | 17 | 9 | 3 | 5 | 21:14 | 7 | 30 | |
| 6. | San Antonio | 17 | 7 | 9 | 1 | 33:20 | 13 | 30 | |
| 7. | Phoenix Rising | 17 | 7 | 7 | 3 | 38:18 | 20 | 28 | |
| 8. | Rio Grande | 17 | 6 | 6 | 5 | 24:25 | -1 | 24 | |
| 9. | Monterey Bay | 17 | 6 | 4 | 7 | 25:24 | 1 | 22 | |
| 10. | El Paso | 17 | 5 | 4 | 8 | 19:23 | -4 | 19 | |
| 11. | Oakland Roots | 17 | 4 | 7 | 6 | 18:18 | 0 | 19 | |
| 12. | Las Vegas Lights | 17 | 2 | 3 | 12 | 20:36 | -16 | 9 |