| # | Eastern Conference | MP | W | D | L | G | GD | Pts | Form |
|---|---|---|---|---|---|---|---|---|---|
| 1. | Tampa Bay | 5 | 4 | 1 | 0 | 15:3 | 12 | 13 | |
| 2. | Louisville City | 5 | 4 | 0 | 1 | 10:6 | 4 | 12 | |
| 3. | Memphis | 5 | 3 | 1 | 1 | 9:5 | 4 | 10 | |
| 4. | Indy Eleven | 5 | 3 | 0 | 2 | 9:8 | 1 | 9 | |
| 5. | Miami FC | 5 | 2 | 2 | 1 | 6:5 | 1 | 8 | |
| 6. | Birmingham | 5 | 2 | 1 | 2 | 8:7 | 1 | 7 | |
| 7. | FC Tulsa | 5 | 2 | 1 | 2 | 10:10 | 0 | 7 | |
| 8. | Hartford Athletic | 5 | 2 | 0 | 3 | 11:11 | 0 | 6 | |
| 9. | Detroit | 5 | 1 | 2 | 2 | 7:5 | 2 | 5 | |
| 10. | Pittsburgh | 5 | 1 | 2 | 2 | 6:6 | 0 | 5 | |
| 11. | Atlanta United 2 | 5 | 1 | 1 | 3 | 6:11 | -5 | 4 | |
| 12. | Loudoun | 5 | 1 | 1 | 3 | 4:14 | -10 | 4 | |
| 13. | New York Red Bulls 2 | 5 | 0 | 1 | 4 | 2:9 | -7 | 1 | |
| 14. | Charleston | 5 | 0 | 1 | 4 | 5:19 | -14 | 1 | |
| # | Western Conference | MP | W | D | L | G | GD | Pts | Form |
| 1. | San Antonio | 5 | 4 | 1 | 0 | 7:3 | 4 | 13 | |
| 2. | Phoenix Rising | 5 | 3 | 1 | 1 | 13:7 | 6 | 10 | |
| 3. | Rio Grande | 5 | 3 | 1 | 1 | 11:5 | 6 | 10 | |
| 4. | Oakland Roots | 5 | 3 | 1 | 1 | 8:6 | 2 | 10 | |
| 5. | New Mexico | 5 | 2 | 3 | 0 | 9:6 | 3 | 9 | |
| 6. | Las Vegas Lights | 5 | 2 | 2 | 1 | 9:5 | 4 | 8 | |
| 7. | San Diego Loyal | 5 | 2 | 2 | 1 | 10:10 | 0 | 8 | |
| 8. | El Paso | 5 | 2 | 0 | 3 | 7:12 | -5 | 6 | |
| 9. | Sacramento Republic | 5 | 1 | 1 | 3 | 5:5 | 0 | 4 | |
| 10. | Colorado Springs | 5 | 1 | 1 | 3 | 5:6 | -1 | 4 | |
| 11. | Ventura County | 5 | 1 | 1 | 3 | 8:10 | -2 | 4 | |
| 12. | Orange County SC | 5 | 0 | 3 | 2 | 6:11 | -5 | 3 | |
| 13. | Monterey Bay | 5 | 0 | 1 | 4 | 2:12 | -10 | 1 |
| # | Eastern Conference | MP | W | D | L | G | GD | Pts | Form |
|---|---|---|---|---|---|---|---|---|---|
| 1. | Miami FC | 10 | 6 | 3 | 1 | 19:7 | 12 | 21 | |
| 2. | Tampa Bay | 10 | 6 | 1 | 3 | 25:9 | 16 | 19 | |
| 3. | Indy Eleven | 10 | 6 | 1 | 3 | 16:17 | -1 | 19 | |
| 4. | Memphis | 10 | 5 | 2 | 3 | 21:11 | 10 | 17 | |
| 5. | Louisville City | 10 | 5 | 2 | 3 | 16:12 | 4 | 17 | |
| 6. | Hartford Athletic | 10 | 5 | 1 | 4 | 22:20 | 2 | 16 | |
| 7. | Detroit | 10 | 4 | 3 | 3 | 13:7 | 6 | 15 | |
| 8. | Birmingham | 10 | 4 | 2 | 4 | 20:17 | 3 | 14 | |
| 9. | FC Tulsa | 10 | 4 | 2 | 4 | 17:17 | 0 | 14 | |
| 10. | Pittsburgh | 10 | 3 | 5 | 2 | 12:10 | 2 | 14 | |
| 11. | Charleston | 10 | 2 | 3 | 5 | 11:24 | -13 | 9 | |
| 12. | Atlanta United 2 | 10 | 2 | 1 | 7 | 11:21 | -10 | 7 | |
| 13. | Loudoun | 10 | 2 | 1 | 7 | 9:26 | -17 | 7 | |
| 14. | New York Red Bulls 2 | 10 | 0 | 3 | 7 | 9:27 | -18 | 3 | |
| # | Western Conference | MP | W | D | L | G | GD | Pts | Form |
| 1. | Rio Grande | 10 | 7 | 1 | 2 | 23:8 | 15 | 22 | |
| 2. | San Antonio | 10 | 6 | 3 | 1 | 13:7 | 6 | 21 | |
| 3. | Oakland Roots | 10 | 5 | 2 | 3 | 14:11 | 3 | 17 | |
| 4. | Sacramento Republic | 10 | 4 | 1 | 5 | 16:10 | 6 | 13 | |
| 5. | Phoenix Rising | 10 | 4 | 1 | 5 | 16:17 | -1 | 13 | |
| 6. | Colorado Springs | 10 | 4 | 1 | 5 | 9:11 | -2 | 13 | |
| 7. | El Paso | 10 | 4 | 1 | 5 | 17:22 | -5 | 13 | |
| 8. | New Mexico | 10 | 3 | 3 | 4 | 13:14 | -1 | 12 | |
| 9. | Las Vegas Lights | 10 | 3 | 3 | 4 | 13:21 | -8 | 12 | |
| 10. | San Diego Loyal | 10 | 3 | 2 | 5 | 15:19 | -4 | 11 | |
| 11. | Monterey Bay | 10 | 3 | 2 | 5 | 14:18 | -4 | 11 | |
| 12. | Ventura County | 10 | 2 | 3 | 5 | 14:17 | -3 | 9 | |
| 13. | Orange County SC | 10 | 1 | 5 | 4 | 10:17 | -7 | 8 |
| # | Eastern Conference | MP | W | D | L | G | GD | Pts | Form |
|---|---|---|---|---|---|---|---|---|---|
| 1. | Tampa Bay | 15 | 10 | 1 | 4 | 36:13 | 23 | 31 | |
| 2. | Miami FC | 15 | 9 | 4 | 2 | 26:10 | 16 | 31 | |
| 3. | Memphis | 15 | 9 | 3 | 3 | 31:14 | 17 | 30 | |
| 4. | Louisville City | 15 | 9 | 3 | 3 | 23:13 | 10 | 30 | |
| 5. | Birmingham | 15 | 8 | 2 | 5 | 34:20 | 14 | 26 | |
| 6. | Pittsburgh | 15 | 6 | 6 | 3 | 18:14 | 4 | 24 | |
| 7. | FC Tulsa | 15 | 7 | 2 | 6 | 24:22 | 2 | 23 | |
| 8. | Detroit | 15 | 5 | 6 | 4 | 18:12 | 6 | 21 | |
| 9. | Hartford Athletic | 15 | 6 | 2 | 7 | 26:27 | -1 | 20 | |
| 10. | Indy Eleven | 15 | 6 | 2 | 7 | 19:26 | -7 | 20 | |
| 11. | Charleston | 15 | 4 | 4 | 7 | 23:37 | -14 | 16 | |
| 12. | Loudoun | 15 | 4 | 1 | 10 | 16:36 | -20 | 13 | |
| 13. | Atlanta United 2 | 15 | 2 | 2 | 11 | 14:38 | -24 | 8 | |
| 14. | New York Red Bulls 2 | 15 | 1 | 3 | 11 | 14:37 | -23 | 6 | |
| # | Western Conference | MP | W | D | L | G | GD | Pts | Form |
| 1. | San Antonio | 15 | 9 | 4 | 2 | 20:12 | 8 | 31 | |
| 2. | San Diego Loyal | 15 | 8 | 2 | 5 | 27:22 | 5 | 26 | |
| 3. | Rio Grande | 15 | 7 | 4 | 4 | 27:14 | 13 | 25 | |
| 4. | Sacramento Republic | 15 | 7 | 2 | 6 | 26:15 | 11 | 23 | |
| 5. | Oakland Roots | 15 | 6 | 4 | 5 | 22:19 | 3 | 22 | |
| 6. | Monterey Bay | 15 | 6 | 2 | 7 | 17:21 | -4 | 20 | |
| 7. | Phoenix Rising | 15 | 5 | 4 | 6 | 21:19 | 2 | 19 | |
| 8. | El Paso | 15 | 5 | 2 | 8 | 20:30 | -10 | 17 | |
| 9. | New Mexico | 15 | 4 | 5 | 6 | 20:24 | -4 | 17 | |
| 10. | Las Vegas Lights | 15 | 4 | 5 | 6 | 16:26 | -10 | 17 | |
| 11. | Colorado Springs | 15 | 4 | 4 | 7 | 19:28 | -9 | 16 | |
| 12. | Orange County SC | 15 | 3 | 7 | 5 | 22:26 | -4 | 16 | |
| 13. | Ventura County | 15 | 3 | 4 | 8 | 24:29 | -5 | 13 |
| # | Eastern Conference | MP | W | D | L | G | GD | Pts | Form |
|---|---|---|---|---|---|---|---|---|---|
| 1. | Louisville City | 20 | 14 | 3 | 3 | 38:16 | 22 | 45 | |
| 2. | Tampa Bay | 20 | 14 | 2 | 4 | 49:19 | 30 | 44 | |
| 3. | Memphis | 20 | 12 | 3 | 5 | 39:19 | 20 | 39 | |
| 4. | Birmingham | 20 | 11 | 3 | 6 | 44:25 | 19 | 36 | |
| 5. | Miami FC | 20 | 10 | 5 | 5 | 31:20 | 11 | 35 | |
| 6. | Pittsburgh | 20 | 9 | 6 | 5 | 28:21 | 7 | 33 | |
| 7. | Detroit | 20 | 7 | 8 | 5 | 22:16 | 6 | 29 | |
| 8. | FC Tulsa | 20 | 8 | 4 | 8 | 29:29 | 0 | 28 | |
| 9. | Hartford Athletic | 20 | 7 | 3 | 10 | 32:36 | -4 | 24 | |
| 10. | Indy Eleven | 20 | 6 | 2 | 12 | 19:35 | -16 | 20 | |
| 11. | Loudoun | 20 | 5 | 2 | 13 | 25:50 | -25 | 17 | |
| 12. | Charleston | 20 | 4 | 4 | 12 | 27:49 | -22 | 16 | |
| 13. | Atlanta United 2 | 20 | 3 | 4 | 13 | 24:52 | -28 | 13 | |
| 14. | New York Red Bulls 2 | 20 | 2 | 4 | 14 | 15:51 | -36 | 10 | |
| # | Western Conference | MP | W | D | L | G | GD | Pts | Form |
| 1. | San Antonio | 20 | 14 | 4 | 2 | 31:13 | 18 | 46 | |
| 2. | San Diego Loyal | 20 | 11 | 2 | 7 | 38:32 | 6 | 35 | |
| 3. | Rio Grande | 20 | 8 | 7 | 5 | 31:18 | 13 | 31 | |
| 4. | Oakland Roots | 20 | 8 | 6 | 6 | 31:25 | 6 | 30 | |
| 5. | Las Vegas Lights | 20 | 8 | 5 | 7 | 25:30 | -5 | 29 | |
| 6. | Sacramento Republic | 20 | 8 | 4 | 8 | 31:23 | 8 | 28 | |
| 7. | Monterey Bay | 20 | 8 | 4 | 8 | 23:24 | -1 | 28 | |
| 8. | El Paso | 20 | 7 | 5 | 8 | 28:32 | -4 | 26 | |
| 9. | New Mexico | 20 | 6 | 8 | 6 | 26:28 | -2 | 26 | |
| 10. | Ventura County | 20 | 6 | 4 | 10 | 34:38 | -4 | 22 | |
| 11. | Colorado Springs | 20 | 6 | 4 | 10 | 28:36 | -8 | 22 | |
| 12. | Phoenix Rising | 20 | 5 | 6 | 9 | 29:31 | -2 | 21 | |
| 13. | Orange County SC | 20 | 4 | 8 | 8 | 29:36 | -7 | 20 |
| # | Eastern Conference | MP | W | D | L | G | GD | Pts | Form |
|---|---|---|---|---|---|---|---|---|---|
| 1. | Tampa Bay | 25 | 17 | 3 | 5 | 61:25 | 36 | 54 | |
| 2. | Louisville City | 25 | 16 | 3 | 6 | 49:24 | 25 | 51 | |
| 3. | Memphis | 25 | 15 | 4 | 6 | 53:23 | 30 | 49 | |
| 4. | Birmingham | 25 | 14 | 4 | 7 | 48:27 | 21 | 46 | |
| 5. | Miami FC | 25 | 11 | 8 | 6 | 38:25 | 13 | 41 | |
| 6. | Pittsburgh | 25 | 10 | 8 | 7 | 33:30 | 3 | 38 | |
| 7. | Detroit | 25 | 9 | 10 | 6 | 31:23 | 8 | 37 | |
| 8. | FC Tulsa | 25 | 9 | 6 | 10 | 35:40 | -5 | 33 | |
| 9. | Hartford Athletic | 25 | 8 | 5 | 12 | 38:43 | -5 | 29 | |
| 10. | Indy Eleven | 25 | 8 | 3 | 14 | 30:45 | -15 | 27 | |
| 11. | Loudoun | 25 | 6 | 3 | 16 | 29:60 | -31 | 21 | |
| 12. | Charleston | 25 | 5 | 6 | 14 | 35:59 | -24 | 21 | |
| 13. | Atlanta United 2 | 25 | 4 | 5 | 16 | 32:64 | -32 | 17 | |
| 14. | New York Red Bulls 2 | 25 | 2 | 5 | 18 | 20:61 | -41 | 11 | |
| # | Western Conference | MP | W | D | L | G | GD | Pts | Form |
| 1. | San Antonio | 25 | 17 | 5 | 3 | 40:19 | 21 | 56 | |
| 2. | San Diego Loyal | 25 | 12 | 5 | 8 | 47:39 | 8 | 41 | |
| 3. | Rio Grande | 25 | 11 | 7 | 7 | 41:27 | 14 | 40 | |
| 4. | Oakland Roots | 25 | 10 | 9 | 6 | 39:31 | 8 | 39 | |
| 5. | Sacramento Republic | 25 | 11 | 5 | 9 | 37:25 | 12 | 38 | |
| 6. | New Mexico | 25 | 10 | 8 | 7 | 39:33 | 6 | 38 | |
| 7. | El Paso | 25 | 10 | 6 | 9 | 36:35 | 1 | 36 | |
| 8. | Monterey Bay | 25 | 10 | 4 | 11 | 33:34 | -1 | 34 | |
| 9. | Colorado Springs | 25 | 9 | 4 | 12 | 40:45 | -5 | 31 | |
| 10. | Las Vegas Lights | 25 | 8 | 7 | 10 | 26:36 | -10 | 31 | |
| 11. | Ventura County | 25 | 8 | 5 | 12 | 41:49 | -8 | 29 | |
| 12. | Phoenix Rising | 25 | 6 | 6 | 13 | 32:46 | -14 | 24 | |
| 13. | Orange County SC | 25 | 4 | 10 | 11 | 34:46 | -12 | 22 |
| # | Eastern Conference | MP | W | D | L | G | GD | Pts | Form |
|---|---|---|---|---|---|---|---|---|---|
| 1. | Louisville City | 30 | 19 | 5 | 6 | 59:27 | 32 | 62 | |
| 2. | Memphis | 30 | 19 | 4 | 7 | 63:28 | 35 | 61 | |
| 3. | Tampa Bay | 30 | 18 | 5 | 7 | 66:31 | 35 | 59 | |
| 4. | Birmingham | 30 | 17 | 5 | 8 | 54:31 | 23 | 56 | |
| 5. | Miami FC | 30 | 14 | 9 | 7 | 44:28 | 16 | 51 | |
| 6. | Detroit | 30 | 13 | 10 | 7 | 41:27 | 14 | 49 | |
| 7. | Pittsburgh | 30 | 13 | 8 | 9 | 42:36 | 6 | 47 | |
| 8. | Indy Eleven | 30 | 12 | 3 | 15 | 39:50 | -11 | 39 | |
| 9. | FC Tulsa | 30 | 10 | 6 | 14 | 43:54 | -11 | 36 | |
| 10. | Hartford Athletic | 30 | 10 | 5 | 15 | 43:50 | -7 | 35 | |
| 11. | Charleston | 30 | 5 | 7 | 18 | 38:70 | -32 | 22 | |
| 12. | Loudoun | 30 | 6 | 3 | 21 | 32:72 | -40 | 21 | |
| 13. | Atlanta United 2 | 30 | 5 | 5 | 20 | 35:79 | -44 | 20 | |
| 14. | New York Red Bulls 2 | 30 | 2 | 6 | 22 | 23:69 | -46 | 12 | |
| # | Western Conference | MP | W | D | L | G | GD | Pts | Form |
| 1. | San Antonio | 30 | 21 | 5 | 4 | 49:22 | 27 | 68 | |
| 2. | San Diego Loyal | 30 | 15 | 6 | 9 | 61:51 | 10 | 51 | |
| 3. | Rio Grande | 30 | 13 | 7 | 10 | 48:35 | 13 | 46 | |
| 4. | El Paso | 30 | 13 | 7 | 10 | 48:39 | 9 | 46 | |
| 5. | Oakland Roots | 30 | 11 | 12 | 7 | 46:38 | 8 | 45 | |
| 6. | Sacramento Republic | 30 | 12 | 8 | 10 | 41:29 | 12 | 44 | |
| 7. | Colorado Springs | 30 | 13 | 4 | 13 | 52:51 | 1 | 43 | |
| 8. | New Mexico | 30 | 11 | 10 | 9 | 42:36 | 6 | 43 | |
| 9. | Las Vegas Lights | 30 | 10 | 9 | 11 | 33:42 | -9 | 39 | |
| 10. | Monterey Bay | 30 | 11 | 4 | 15 | 36:50 | -14 | 37 | |
| 11. | Ventura County | 30 | 10 | 6 | 14 | 49:58 | -9 | 36 | |
| 12. | Phoenix Rising | 30 | 10 | 6 | 14 | 41:51 | -10 | 36 | |
| 13. | Orange County SC | 30 | 6 | 12 | 12 | 45:54 | -9 | 30 |